Hereditary tissues out of exact same-sex sexual choices
One of pairs of individuals in the united kingdom Biobank associated during the full cousin or better [because the acquiesced by genomic resemblance (14); n sets = 106,979], a lot more directly associated citizens were prone to feel concordant for the terms of same-intercourse sexual conclusion. From the acting the brand new communications out of relatedness certainly one of anyone while the similarity of the sexual conclusion, we projected wider-sense heritability-brand new portion of type inside the a characteristic attributable to genetic adaptation-on thirty two.4% [95% trust menstruation (CIs), 10.6 so you can 54.3] (dining table S4). It imagine are in keeping with earlier in the day estimates out-of quicker dual degree (7).
To increase power and generalizability of our results, we also performed a GWAS in the cohort from 23andMe using an equivalent variable (individuals who reported having had sex with “Other sex only” versus the other options on a seven-point scale regarding participants’ sexual partners) (n = 68,527 individuals, of which 12,933 reported same-sex sexual behavior) (table S3) (14). We estimated the genetic correlation (16) between different heritable traits to determine the degree of consistency of genetic influences on same-sex sexual behavior in the two studies, which was high [genetic correlation coefficient (rg) = 0.87; 95% CIs, 0.67 to 1.06] (table S5) (14). Sigue leyendo